Bioperl 1.5.0 released

Bioperl 1.5.0 Developer’s release is available for download.

We’ll update the website to reflect this new release.

The odd-numbered releases are called developer releases and are not
deposited on CPAN. Please note that the API in 1.5.0 may change before
the 1.6.0 release. which will be consider a stable API. We may do
another developer release before 1.6.0 goes out.

Lots of people have contributed to this release, I apologize for not
naming them all. I’ll try to cover some: thanks to Aaron Mackey for
getting this release started, Brian Osborne for extensive documentation
improvements, Nathan Haigh for volunteering to make a PPM of the
release and Barry Moore and Nathan answering many of the windows
related questions, Allen Day & Scott Cain & Steffen Grossmann for the
work on FeatureIO, GFF3, and SeqFeature::Annotated, Chris Mungall for
the work with Unflattener to merge GenBank annotations into GFF3

Please see the AUTHORS file for a complete list of contributors.

Jason Stajich on behalf of the Bioperl developers.

Here is the info from the Changes file.
1.5 Developer release

  • Bio::Align::DNAStatistics and Bio::Align::ProteinStatistics provide Jukes-Cantor and Kimura pairwise distance methods, respectively.
  • Bio::AlignIO support for “po” format of POA, and “maf”; Bio::AlignIO::largemultifasta is a new alternative to Bio::AlignIO::fasta for temporary file-based manipulation of particularly large multiple sequence alignments.
  • Bio::Assembly::Singlet allows orphan, unassembled sequences to be treated similarly as an assembled contig.
  • Bio::CodonUsage provides new rare_codon() and probable_codons() methods for identifying particular codons that encode a given amino acid.
  • Bio::Coordinate::Utils provides new from_align() method to build a Bio::Coordinate pair directly from a Bio::Align::AlignI-conforming object.
  • Bio::DB::Biblio::eutils is a class for querying NCBI’s Eutils. Send a Pubmed, Pubmed Central, Entrez, or other query to NCBI’s web service using standard Pubmed query syntax, and retrieve results as XML.
  • Bio::DB::GFF has various sundry bug fixes.
  • Bio::FeatureIO is a new SeqIO-style subsystem for writing/reading genomic features to/from files. I/O classes exist for BED, GTF (aka GFF v2.5), and GFF v3. Bio::FeatureIO classes only read/write Bio::SeqFeature::Annotated objects. Notably, the GFF v3 class requires features to be typed into the Sequence Ontology.
  • Bio::Graph namespace contains new modules for manipulation and analysis of protein interaction graphs.
  • Bio::Graphics has many bug fixes and shiny new glyphs.
  • Bio::Index::Hmmer and Bio::Index::Qual provide multiple-file
    indexing for HMMER reports and FASTA qual files, respectively.

  • Bio::Map::Clone, Bio::Map::Contig, and Bio::Map::FPCMarker are
    new objects that can be placed within a Bio::Map::MapI-compliant
    genetic/physical map; Bio::Map::Physical provides a new physical
    map type; Bio::MapIO::fpc provides finger-printed clone mapping

  • Bio::Matrix::PSM provide new support for postion-specific
    (scoring) matrices (e.g. profiles, or “possums”).

  • Bio::Ontology::Ontology and Bio::Ontology::Term objects can now
    be instantiated without explicitly using Bio::OntologyIO. This
    is possible through changes to Bio::Ontology::OntologyStore to
    download ontology files from the web as necessary. Locations of
    ontology files are hard-coded into

  • Bio::PopGen includes many new methods and data types for
    population genetics analyses.

  • New constructor to Bio::Range, unions(). Given a list of
    ranges, returns another list of “flattened” ranges —
    overlapping ranges are merged into a single range with the
    mininum and maximum coordinates of the entire overlapping group.

  • Bio::Root::IO now supports -url, in addition to -file and -fh. The new -url argument allows one to specify the network address of a file for input. -url currently only works for GET requests, and thus is read-only.
  • Bio::SearchIO::hmmer now returns individual Hit objects for each domain alignment (thus containing only one HSP); previously separate alignments would be merged into one hit if the domaini nvolved in the alignments was the same, but this only worked when the repeated domain occured without interruption by any other domain, leading to a confusing mixture of Hit and HSP objects.
  • Bio::Search::Result::ResultI-compliant report objects now implement the “get_statistics” method to access Bio::Search::StatisticsI objects that encapsulate any statistical parameters associated with the search (e.g. Karlin’s lambda for BLAST/FASTA).
  • Bio::Seq::LargeLocatableSeq combines the functionality already found in Bio::Seq::LargeSeq and Bio::LocatableSeq.
  • Bio::SeqFeature::Annotated is a replacement for Bio::SeqFeature::Generic. It breaks compliance with the Bio::SeqFeatureI interface because the author was sick of dealing with untyped annotation tags. All Bio::SeqFeature::Annotated annotations are Bio::AnnotationI compliant, and accessible through Bio::Annotation::Collection.
  • Bio::SeqFeature::Primer implements a Tm() method for primer melting point predictions.
  • Bio::SeqIO now supports AGAVE, BSML (via SAX), CHAOS-XML, InterProScan-XML, TIGR-XML, and NCBI TinySeq formats.
  • Bio::Taxonomy::Node now implements the methods necessary for Bio::Species interoperability.
  • Bio::Tools::CodonTable has new reverse_translate_all() and make_iupac_string() methods.
  • Bio::Tools::dpAlign now provides sequence profile alignments.
  • Bio::Tools::GFF now parses GFF version 2.5 (a.k.a. GTF).
  • Bio::Tools::Fgenesh, Bio::Tools::tRNAscanSE are new report parsers.
  • Bio::Tools::SiRNA includes two new rulesets (Saigo and Tuschl) for designing small inhibitory RNA.
  • Bio::Tree::DistanceFactory provides NJ and UPGMA tree-building methods based on a distance matrix.
  • Bio::Tree::Statistics provides an assess_bootstrap() method to calculate bootstrap support values on a guide tree topology, based on provided bootstrap tree topologies.
  • Bio::TreeIO now supports the Pagel (PAG) tree format.