About the OBF

The Open Bioinformatics Foundation (OBF) is a non-profit, volunteer-run group that promotes open source software development and Open Science within the biological research community. Membership in the OBF is free and open to anyone who wants to help promote open source or open science in a biological field.

OBF runs the annual Bioinformatics Open Source Conference (BOSC).

BOSC 2025 took place July 21-22, 2025, in Liverpool, UK (as part of ISMB/ECCB 2025). BOSC 2026 will be part of ISMB 2026 in Washington, DC.

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Poster session at GCCBOSC2018

OBF Treasurer Heather Wiencko introducing OBF at BOSC 2024

OBF Event Awards

The OBF Event Fellowship program aims to increase diverse participation at events promoting open source bioinformatics software development and open science in the biological research community.

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Ruth Nanjala, an OBF Event Award winner, by her poster

Call for Nominations: BOSC 2026 Keynote Speakers

Chris Mungall keynote - BOSC 2025

BOSC 2026 is planned for July 14-15, 2026, as part of ISMB 2026 in Washington, DC.

We invite our community to nominate potential keynote speakers who would be of interest to our community. You may submit as many nominations as you wish. The form may be filled out multiple times. Please submit nominations by December 15, 2025.

Why this matters

Keynote talks are always a highlight at BOSC. We traditionally open and close the conference with invited speakers—prominent contributors or emerging leaders whose work resonates with the bioinformatics open-source community.

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BioHackathon Europe 2025: A Week full of Brainstorming, Coding & Collaboration

The Open Bioinformatics Foundation (OBF) Event Fellowship program aims to promote diverse participation at events promoting open-source bioinformatics software development and open science practices in the biological research community. Hetvi J, a PhD student at Imperial College London, was awarded an OBF Event Fellowship to attend BioHackathon Europe 2025.

Thanks to the Event Fellowship from the Open Bioinformatics Foundation (OBF), I had the opportunity to attend BioHackathon Europe 2025 located in the beautiful city of Bad Saarow, Germany. I’m currently a 3rd year PhD student in Biostatistics and my work focuses on human mitochondrial genetics. Specifically, I construct statistical models to test whether the presence or absence of somatic mitochondrial variants is associated with gene expression changes indicative of stress and aging. As part of my PhD, I work with single-cell -omics data, and run bioinformatics pipelines over high performance computing systems. My broader interests in the fields of open-source scientific computing and bioinformatics motivated me to participate in this hackathon.

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2025 ESIIL Innovation Summit: Collaborative and Open Environmental Data Science in Boulder

The Open Bioinformatics Foundation (OBF) Event Fellowship program aims to promote diverse participation at events promoting open-source bioinformatics software development and open science practices in the biological research community. Ruby Krasnow, a PhD student at the University of Maine, was awarded an OBF Event Fellowship to attend the 2025 ESIIL Innovation Summit. A group photo of six researchers (three men and three women) taken in a classroom. A draft food web is visible on the whiteboard behind them. My team (Group 4) from the 2025 ESIIL Innovation Summit.

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Biopython 1.86 released

Biopython 1.86 has been released and is available from our website and PyPI.

This contains about nine months worth of updates, and is our first release with Python 3.14 support. See change-log in the news file (most of the changes are in Bio.Align and Bio.PDB). There have also been a few deprecations and removals of older code.

Many thanks to the Biopython developers and community for making this release possible, especially the following contributors who were happy to be named:

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Call for the third 2025 round of the OBF Event Fellowship & overview of the second round of 2025

The call for applications for round 3 of the OBF Event Fellowship for 2025 is now open. The deadline for this round is 1 December 2025. You can submit your application through this Google Form. We have provided a Word template to help you draft the application locally before filling out the form – make a copy of this template.

The Open Bioinformatics Foundation (OBF)’s Event Fellowship program is aimed at increasing diverse participation at events promoting open science in the bioinformatics and biological research communities. Awards are made three times a year; the next deadline is December 1, 2025.

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GigaScience: 15 years of great open science publishing & the end of an era?

To begin something is difficult; to keep something going is a different challenge. Even when it is the right thing to do, if it does not yield economic benefit in the short term, it may be difficult to sustain. Open science, including open-source software development and open data, is precisely such an example. Everyone agrees these are of great importance, yet when confronted with the immediate demands of an academic career or the short-term profit of a company, putting in the extra work to make all of the code and data publicly accessible and reusable may not be a priority. That is why individuals and organizations that not only embrace these principles but also persist with them over long periods are worthy of being recognized. They act not merely for themselves, but for the whole of human society. Photo at GigaScience Birthday Party 2025 - Scott cutting the cake

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ISMB/ECCB 2025: Liverpool, LLMs and Lessons in Open Science

The Open Bioinformatics Foundation (OBF) Event Fellowship program aims to promote diverse participation at events promoting open-source bioinformatics software development and open science practices in the biological research community. Muhamad Haries Ramdhani, a PhD Student at the University of Aberdeen, was awarded an OBF Event Fellowship to attend ISMB/ECCB 2025. Keynote speakers and DREAM challenges talks at the ISMB/ECCB

The Journey to Liverpool

I had heard about ISMB before, but I wasn’t entirely clear on its joint conference format with ECCB. What I did know was that ISMB/ECCB is arguably the biggest conference for computational biology in the world. For months, my attendance felt uncertain, as I initially didn’t know if the 2025 edition would be held in the UK. When the location was confirmed as Liverpool, it was a huge relief. Being a UK-based student meant I was fortunate enough to avoid a lengthy and often stressful visa application process.

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ISMB 2025: A Week of Learning, Teaching, and Connecting in Liverpool

The Open Bioinformatics Foundation (OBF) Event Fellowship program aims to promote diverse participation at events promoting open-source bioinformatics software development and open science practices in the biological research community. Tayyaba Alvi, a PhD student at Fritz Lipmann Institute on Aging, was awarded an OBF Event Fellowship to attend ISMB/ECCB2025. David Baker on the screen on the left, and me with my poster on the right

Thanks to the Event Fellowship from the Open Bioinformatics Foundation (OBF), I had the chance to attend the 33rd Conference on Intelligent Systems for Molecular Biology (ISMB 2025) in Liverpool. It’s the annual meeting of the International Society for Computational Biology (ISCB) and the biggest conference in the field. This year, it brought together over 2,000 researchers from all over the world at ACC Liverpool, a beautiful venue right by the Albert Dock.

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Call for the second 2025 round of the OBF Event Fellowship & overview of the first round of 2025

The call for applications for round 2 of the OBF Event Fellowship for 2025 is now open. The deadline for this round is 1 August 2025. You can submit your application through this Google Form. We have provided a Word template to help you draft the application locally before filling out the form – make a copy of this template.

The Open Bioinformatics Foundation (OBF)’s Event Fellowship program is aimed at increasing diverse participation at events promoting open science in the bioinformatics and biological research communities. Awards are made three times a year; the next deadline is August 1, 2025.

[Read More]