About the OBF

The Open Bioinformatics Foundation (OBF) is a non-profit, volunteer-run group that promotes open source software development and Open Science within the biological research community. Membership in the OBF is free and open to anyone who wants to help promote open source or open science in a biological field.

OBF runs the annual Bioinformatics Open Source Conference (BOSC).

BOSC 2025 took place July 21-22, 2025, in Liverpool, UK (as part of ISMB/ECCB 2025). BOSC 2026 will be part of ISMB 2026 in Washington, DC.

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Poster session at GCCBOSC2018

OBF Treasurer Heather Wiencko introducing OBF at BOSC 2024

OBF Event Awards

The OBF Event Fellowship program aims to increase diverse participation at events promoting open source bioinformatics software development and open science in the biological research community.

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Ruth Nanjala, an OBF Event Award winner, by her poster

BioRuby 1.4.3.0001 Released

We are pleased to announce the release of BioRuby 1.4.3.0001. This new release fixes the following bugs.

  • “gem install bio” failed with Ruby 2.0 or later versions.
  • lib/bio/db/gff.rb script encoding issue
  • Bio::Blast::Default::Report parse error when subject sequence contains spaces.

For more information, see RELEASE_NOTES.rdoc and ChangeLog.

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Biopython 1.61 released

Source distributions and Windows installers for Biopython 1.61 are now available from the downloads page on the Biopython website and from the Python Package Index (PyPI).

The updated Biopython Tutorial and Cookbook is online ( PDF).

Platforms/Deployment

We currently support Python 2.5, 2.6 and 2.7 and also test under Python 3.1, 3.2 and 3.3 (including modules using NumPy), and Jython 2.5 and PyPy 1.9 (Jython and PyPy do not cover NumPy or our C extensions). We are still encouraging early adopters to help test on these platforms, and have included a ‘beta’ installer for Python 3.2 (and Python 3.3 to follow soon) under 32-bit Windows.

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Minutes:2012 Nov ConfCall

Agenda

  1. Old business
  2. New business
    1. Election of new Board members. Nominated candidate is Chris Fields.
    2. Review and possibly revamping of the procedure for joining and maintaining the OBF membership
    3. Asset transfer to SPI

Minutes

Venue: held by conference call Nov 13, 2012, 11.30am EST (16:30 UTC)

Attending:

  • Directors: Jason Stajich, Nomi Harris, Peter Cock, Hilmar Lapp
  • Guests: Scott Markel, Chris Fields

Minutes:

Hilmar called meeting to order at 11:34am EST.

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OBF Board meeting 13 Nov

The Open Bioinformatics Foundation (OBF) will be holding a public Board of Directors meeting on Tuesday, 13 Nov, 2012, at 11.30am EST (8.30am PST, 17:30 CET, 16:30 UTC/GMT).

The meeting will be held online or over conference call. We will post details about how to dial in or connect closer to the date ( here).

On the agenda Richard Holland and Chris Fields are running for election to the Board, and some other items primarily up for discussion, including how to keep our membership roll up-to-date and increasing with the least barriers. We will post a more detailed agenda in advance of the meeting ( here).

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Server transition process to AWS servers

Our aging server which has run for 5+ years the OBF sites has finally reached end of its lifespan. We are currently migrating sites to AWS volumes and sites for a temporary period while we decide about how to continue to support these services in the future.  There will be some downtime while the all-volunteer OBF admin team makes time to fix this.

Nearly all projects use public source code repositories such as github or sourceforge so no problems with access to the code should be limiting. Mailing lists are still using the old server but will be moved to the AWS site in the next few days and we are working to have little downtime for the lists.  Mediawiki sites are moving in stages and so far Bioperl, Biopython, and the OBF wikis have been migrated.  This news site has also been migrated to AWS and this is the 1st post from it (will it work!?)

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OBF is now an SPI-associated project

I am very pleased to announce that the Open Bioinformatics Foundation (O|B|F) is now a Software in the Public Interest (SPI) associated project, rather than its own not-for-profit incorporation.

An electronic vote of O|B|F members on whether or not to provisionally approve the invitation from SPI closed yesterday at 19:00 UTC. We had a participation of 39 out of 105 eligible, or 37%, which is far above the quorum of 10%. The tally is 38 for provisionally accepting and 1 against. The tally can be seen (and audited) here: https://vote.heliosvoting.org/helios/e/OBFjoiningSPI

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Minutes:2012 Sep ConfCall

Agenda

  1. Old business
  2. New business
    1. Approval of changes to O|B|F Bylaws

Minutes

Venue: held by WebEx conference with audio bridge through phone (donated by BioTeam), scheduled for Sep 11, 2012, 11.30am EDT (15:30 UTC)

Attending:

  • Directors: Hilmar Lapp, Nomi Harris, Chris Dagdigian, Jason Stajich, Peter Cock
  • Guests: Scott Markel

Minutes:

Hilmar called meeting to order at 11:38am EDT.

Old business:

New business:

i. Approval of changes to O|B|F Bylaws.

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BioRuby 1.4.3 released

We are pleased to announce the release of BioRuby 1.4.3. This new release fixes bugs existed in 1.4.2 and improves portability on JRuby and Rubinius.

Here is a brief summary of changes.

  • Bio::KEGG::KGML bug fixes and new class Bio::KEGG::KGML::Graphics for storing a graphics element.
  • Many failures and errors running on JRuby and Rubinius are resolved.
  • Strange behavior related with “circular require” is fixed.
  • Fixed: Genomenet remote BLAST does not work.
  • Fixed: Bio::NucleicAcid.to_re(“s”) typo.
  • Fixed: Bio::EMBL#os raises RuntimeError.
  • Fixed: bin/bioruby: Failed to save object with error message “can’t convert Symbol into String” on Ruby 1.9.

In addition, many changes have been made, including incompatible changes. For more information, see RELEASE_NOTES.rdoc and ChangeLog.

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Travis-CI for Testing

Earlier this year BioRuby and then Biopython and BioPerl started using Travis-CI.org, a hosted continuous integration service for the open source community, to run their unit tests automatically whenever their GitHub repositories are updated:

The BioRuby team are also using Travis-CI for automated testing of their new ‘plugin’ ecosystem, BioRuby Gems, or BioGems.

Travis-CI gives us continuous testing, but for the moment only covers one operating system (currently 32 bit Ubuntu Linux using Virtual Machines). This automated testing is therefore complementary to our existing OBF BuildBot server which aims to run nightly tests on volunteer developer machines setup to cover a broad range of operating systems and configurations.

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Biopython 1.60 released

Source distributions and Windows installers for Biopython 1.60 are now available from the downloads page on the Biopython website and from the Python Package Index (PyPI).

Platforms/Deployment

We currently support Python 2.5, 2.6 and 2.7 and also test under Jython 2.5 and PyPy 1.9 (which does not cover NumPy or our C extensions). Please note that Python 2.4 or earlier is not supported.

Most functionality is also working under Python 3.1 and 3.2 (including modules using NumPy). We are now encouraging early adopters to help beta testing on these platforms, and have included a ‘beta’ installer for Python 3.2 under 32-bit Windows.

[Read More]