We are pleased to announce the release of Biopython 1.41. Many improvements were made in Biopython during the eight months since the previous release, and the new release contains lots of bugfixes, improvements, new functionalities, and better documentation. To pick a few, there’s the new Bio.MEME module by Jason Hackney, updates to the Blast parser using Bertrand Frottier’s NCBIXML code, a BLAT parser by Yair Benita, numerous updates in Bio.PDB, CompareACE support in AlignAce, and improved user-friendliness in Bio.Seq.
[Read More]About the OBF
The Open Bioinformatics Foundation (OBF) is a non-profit, volunteer-run group that promotes open source software development and Open Science within the biological research community. Membership in the OBF is free and open to anyone who wants to help promote open source or open science in a biological field.
OBF runs the annual Bioinformatics Open Source Conference (BOSC).
BOSC 2025 took place July 21-22, 2025, in Liverpool, UK (as part of ISMB/ECCB 2025). BOSC 2026 will be part of ISMB 2026 in Washington, DC.


OBF Event Awards
The OBF Event Fellowship program aims to increase diverse participation at events promoting open source bioinformatics software development and open science in the biological research community.

Bioperl 1.5.1
I am pleased to announce the 1.5.1 developer release of Bioperl.
Essential links here Core http://bioperl.org/DIST/bioperl-1.5.1.tar.gz http://bioperl.org/DIST/bioperl-1.5.1.zip http://bioperl.org/DIST/bioperl-1.5.1.tar.bz2
Run http://bioperl.org/DIST/bioperl-run-1.5.1.tar.gz http://bioperl.org/DIST/bioperl-run-1.5.1.zip http://bioperl.org/DIST/bioperl-run-1.5.1.tar.bz2
Ext http://bioperl.org/DIST/bioperl-ext-1.5.1.tar.gz http://bioperl.org/DIST/bioperl-ext-1.5.1.zip http://bioperl.org/DIST/bioperl-ext-1.5.1.tar.bz2
MD5 sum http://bioperl.org/DIST/SIGNATURES.md5
Please see my mailing list post for more information.
[Read More]Bioperl 1.5.1 RC4
Release Candidate 4 for bioperl 1.5.1 (Developer release) core, run, and ext packages is available.
Several bug fixes went in last week so I’ve made what I hope to be the last release candidate before 1.5.1 goes out.
More Info: http://portal.open-bio.org/pipermail/bioperl-l/2005-October/019904.html
[Read More]O|B|F Board of Directors Meeting
The 2005 Board of Directors meeting for the Open Bioinformatics Foundation was held on Thursday, June 24th 2005 in Detroit, MI USA at the site of the BOSC2005 meeting.
This was a major meeting and represents the first attempt to build a governance platform for the organization as well as set up the mechanism for building a voting membership. The O|B|F members will be able to direct the operation of the organization and will also be able to join the Board.
Other major news from the meeting: - Ewan Birney steps down as president; joins Board as at-large member - Jason Stajich joins board and is elected President - Hilmar Lapp is elected to a new position of ‘Parlimentarian’ - Determined efforts to build a voting membership body
Links to meeting minutes and Election Bylaws follow are below …
[Read More]site updated prior to server move
The backend MovableType software powering this site was upgraded and the backend storage was switched from berkelyDB to SQL. These preparations are being done to ease the transition of http://news.open-bio.org to a new server. The primary purpose of this news entry is to confirm that the posting system still works after the upgrade!
Minutes:2005 BOSC Meeting
Venue: Renaissance Center in Detroit, on the first floor next to the Starbucks. Date: June 23, 2005, 16:15.
Call to order:
- Board members present: Chris, Hilmar, Ewan, Andrew
- Others: Jason Stajich
Chris / Treasurer’s Report
- Review of the accounts / passing the statements around
- Summary of response to the fraud attempt
- Request to activate the debit card. Granted.
- The account got a $9,000 deposit but we don’t know who it comes from. Chris will investigate.
- We have not yet received our money from the Glasgow BOSC. Chris will follow up on that.
- Chris will pull the current credit report for Open Bio.
- Develop a succession / “hit by the bus” plan for hardware and people. Eg, can we get access to the account if Chris decides to be a beach bum in the S. Pacific?
- We did not pay Delaware to renew our corporate registration. Chris will look into getting the right person to fix that and pay any penalties.
- Some discussion about letting Chris make minor (<$1,000) payments without a counter-signature. Hilmar pointed out that’s in the new bylaws
New Bylaws, Membership
Hilmar presentation of the new OBF bylaws. We reviewed it and made comments. Some time later he finished.
[Read More]BOSC Schedule Posted
PopGen HOWTO
A PopGen HOWTO added to the website for using the population genetics modules in Bioperl.
The PAML HOWTO is in-process of being updated to describe the new functionalilty.
Biopython 1.40 beta released
We are pleased to announce the release of Biopython 1.40 beta. It has been nine months since the last official release (1.30), and there are numerous changes, bugfixes, enhancements, goodies and new contributors. Most notable are the addition of the Nexus parser (Frank Kauff w/ Cymon Cox), the CAPS module (Jonathan Taylor), the Restriction enzyme package (Frederic Sohm), hefty improvements to Bio.PDB (Thomas Hamelryck), MutableSeq (Michiel de Hoon), and more. The delay in the release was caused by day jobs creeping into the lives of most core developers. So we are very happy with this release finally out, and we hope to have the non-beta out soon.
[Read More]