About the OBF

The Open Bioinformatics Foundation (OBF) is a non-profit, volunteer-run group that promotes open source software development and Open Science within the biological research community. Membership in the OBF is free and open to anyone who wants to help promote open source or open science in a biological field.

OBF runs the annual Bioinformatics Open Source Conference (BOSC).

BOSC 2025 took place July 21-22, 2025, in Liverpool, UK (as part of ISMB/ECCB 2025). BOSC 2026 will be part of ISMB 2026 in Washington, DC.

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Poster session at GCCBOSC2018

OBF Treasurer Heather Wiencko introducing OBF at BOSC 2024

OBF Event Awards

The OBF Event Fellowship program aims to increase diverse participation at events promoting open source bioinformatics software development and open science in the biological research community.

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Ruth Nanjala, an OBF Event Award winner, by her poster

Ontology overhaul: migration to 1.2 branch imminent

This is the last call for people to test drive and/or criticize the Bio::Ontology & Bio::OntologyIO re-design and implementation.

The interfaces and modules to look at comprise of Bio::Ontology::OntologyI, Bio::Ontology::TermI, and Bio::OntologyIO. If you care about implementations (as Aaron says most people do rather than bothering with interfaces), check out Bio::Ontology::Ontology, Bio::Ontology::Term, and Bio::OntologyIO.

[Read More]

Prototype of a new biopython.org website

Brad has been working hard on trying to put together a new biopython.org page that incorporates the open-bio news server and the look and feel of the upcoming open-bio page. [Read More]

Working on the Biopython Website

Brad is working on an update of the Biopython website and is so obsessed with it that he is working on it during his minimal lunch time in which he should be enjoying the nice friendly sunshine of a Georgia friday. [Read More]

BioPerl List Summary - January 2003

As I seem to be volunteering for more and more BioPerl documentation jobs recently, I thought I’d pool my resources and recycle some of my tuits to write a list summary. Expect these to be sporadic and incomplete; my goal is to highlight important questions, changes, fixes, and proposals, not recapitulate all list traffic. [Read More]

PostgreSQL issues with bioperl-db

Hilmar writes:

Here’s the background.

The current code in the bioperl-db adaptors to biosql run the connection with AutoCommit off, which means the client determines the transaction. Load_seqdatabase.pl (the main script for loading databases into biosql) treats one sequence entry as one transaction. If any sql statement required for loading the sequence fails unexpectedly, the whole transaction is rolled back, otherwise it is committed once the entry and all its annotation went in successfully. The emphasis rests on ‘unexpectedly’: INSERTs may fail due to unique key violations, which is caught and triggers a look-up of the affected entry by unique key. E.g. a dbxref may already exist; if so, it needs to be looked up in order to establish the association with the bioentry.

[Read More]

Major Bio::Ontology overhaul

Hilmar writes:

Triggered by what happened during the hackathon in Singapore, the Bioperl Ontology object model needs to undergo a number of changes that I’m going to describe below, along with a proposal how to resolve the issues. I have largely implemented the proposal and barring major objections I’m ready to commit tonight or tomorrow morning. Even though some of these things significantly change the API, we (I, backed by the core people) propose to migrate these changes over to the ‘stable’ 1.2 branch, to be able to release bioperl-db (bridges to the biosql schema) in dependency on a stable bioperl branch.

[Read More]

TECHNICAL REPORT ON MOBY WEB MESSAGING LAYER

Date: February 24, 2003 Author: Lincoln Stein Version: early

This report concerns the messaging layer of the Moby project, that point at which semantic information is exchanged between the data consumer (i.e. the biologist) and the data provider (i.e. the model organism system administrator).

[Read More]